You can enable ReplayEngine while debugging CUDA code; that is, ReplayEngine record mode works on the Linux x86-64 host. However, ReplayEngine does not support replay operations when focused on a CUDA thread since it does not support the GPU architecture itself. If you attempt this, you will receive a Not Supported error.
ReplayEngine and Expression Evaluation
The TotalView features that evaluate expressions, including Eval points, the Expression Window, the Variable Window, and the Expression List Window, do still function with ReplayEngine enabled, but there are limitations. Please see “Expression Evaluation with ReplayEngine” in the TotalView for HPC User Guide.